CV
Name
Denis Drainas
Position
Academic Position
Professor of Biochemistry
Head of the Department of Biochemistry
Director of the Unit for Special Biochemiscal Analyses
Εducation and Positions
BSc in Biology, Univ. of Athens 1975
PhD in Biochemistry, University of Glasgow, UK 1978
Research Interests
Studies on RNase P from fungi, bacteria and human cell lines
RNase P as target for the development of novel inhibitors
RNase P as a tool in gene therapy
Representative publications
1. Kalavrizioti D, Vourekas A, Stamatopoulou V, Toumpeki C, Giannouli S, Stathopoulos C, and Drainas D. (2006) RNA-mediated therapeutics: from gene inactivation to clinical application. Current Topics in Med. Chem. 6, 1737-1758.
2. Vourekas A, Kalavrizioti D, Zarkadis IK, Spyroulias GA, Stathopoulos C, and Drainas D. (2007). Identification of a gene that encodes a 40.7 kDa protein associated with Dictyostelium discoideum ribonuclease P holoenzyme. Biochimie, 89, 301-310.
3. Kalavrizioti D, Vourekas A, and Drainas D. (2007) DRpp20 and DRpp40, two protein subunits of ribonuclease P from Dictyostelium discoideum. Gene 400, 52-59.
4. Toumpeki C, Vourekas A, Kalavrizioti D, Stamatopoulou V, and Drainas.D. (2008) Activation of bacterial Ribonuclease P by macrolides. Biochemistry 47(13), 4112-4118.
5. Magoulas G, Papaioannou D, Papadimou E, and Drainas D. (2009) Preparation of spermine conjugates with acidic retinoids with potent ribonuclease P inhibitory activity. Eur. J. Med. Chem. 2009 Jun;44(6):2689-95
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